Looks like someone got the answer to the perennial query!
A new study conducted by researchers at Oregon National Primate Research Center, US indicates that in obesity the brain is unaware of body fat!
In both humans and mice, fat cells throughout the body release a hormone called leptin. This hormone controls sensations like appetite and thirst on reaching the brain.
In theory, when fat increases in the body so do levels of leptin, causing a decrease in appetite. But scientists have found that administering leptin does not reliably work to treat obesity. It is because the high fat diet makes the brain insensitive to leptin and hence oblivious of presence of fats.
The experiment conducted on mice surely works up sympathy for those fat human beings out there!
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